ABSTRACT
The higher respiratory work and less inspiratory muscle strength of patients with cardiac failure may contribute to dicrease their functional capacity. To assess the effects of non invasive intermittent mechanical ventilation on clinical parameters, peropheral perfusion, cardiac and inspiratory muscle function. Patients with chronic cardiac failure, functional cpacity III-IV were subjected to 6 sessions of nasal non invasive intermittent ventilation during 4 hours or to simulated ventilation (controls). Fifteen ventilated patients and 6 controls completed the protocol. Ventilated patients improved the mahler transition score for dysnea by 4ñ1.6 points. They also improved their aerobic capacity, increasing the exercise duration from 10.9ñ4 to 12.7ñ5 min and their maximal oxygen consumption from 14.6ñ4 to 16.4ñ5.7 ml/kg/min. These patients also decreased their O2 and CO2 ventilatory equivalents. Maximal inspiratory pressure increased from 67.9ñ23.6 to 80.19ñ21.4 cm H2O, sustained maximal inspiratory pressure increased from 101.4ñ48 to 133ñ53 cm H2O and maximal endurance increased from 132ñ52 to 162ñ58 g in ventilated patients. None of these variables was modified in control patients. No changes were observed in renal function, blood volume, arterial gases, spirometry or plasma catecholamine levels in any group. Intermittent nasal ventilation or other measures to improve inspiratory muscle function may be beneficial for patients with severe cardiac failure
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Heart Failure/therapy , Respiration, Artificial/methods , Neurotransmitter Agents/physiology , Respiratory Muscles/physiopathology , Clinical Protocols , Ventilation-Perfusion Ratio/physiology , Respiratory Function Tests/methodsABSTRACT
Between august 1991 and august 1993, 75 patients (42 male) with Wolff Parkinson White syndrome (43 concealed) were subjected to radiofrequency ablation of accesory pathway at our institution. 55 had left, 8 postero septal, 2 anteroseptal and 10 right accesory pathways. A retrograde aortic technique with placement of the ablation catheter in close proximity to the mitral annulus was used for most of the patients with left accesory pathways and for some with posteroseptal pathways were ablated using a right heart approach placing the ablation catheter in the tricuspid annulus. Ablation was successful in 61 patients (81 per cent ). One subject developed a fatal cardiac tamponade after a transeptal catheterization and was unrelated to the ablation per se. It is concluded that radiofrequency ablation of accesory pathways is a curative procedure for a great majority of patients with Wolf Parkinson White syndrome